A breakthrough in skin barrier repair developed to help restore normal flush response and durable hydration in rosacea patients with skin characterised by pronounced dryness, irritation and accelerated aging.
- serum-balm texture forms a liquid, breathable bandage on skin
- sets to an intensely hydrating, residue-free finish
- resolves tightness, flaking and peeling
- progressively reduces redness, burning and stinging
- matrix metalloproteinase inhibitors help increase firmness
- improves impression of facial fullness
- reduces visibility of pores which appear open due to chronic irritation
- suitable for use around the eyes
- intended for overnight use
Deuterium Oxide — naturally occurring form of water with heavier hydrogen, making it more resistant to evaporation.
Ceramides — contains an unprecedented combination of newly available skin-identical ceramides made possible by a formula intended for overnight use only.
Essential Fatty Acids — enhance and stabilise skin's ability to produce ceramides.
Biosaccharides — bind water and exert anti-inflammatory effects with high performance and suitability around the eyes.
Ilomastat — broad-spectrum matrix metalloproteinase inhibitor, reduces collagen breakdown to build firmness.
Polyglucuronate — superior to sodium hyaluronate in overnight use application.
Phospholipids — reinforce fragile skin cell structure.
Betaglucan and Schizophyllan — profoundly soothing and anti-inflammatory, stimulate the skin's immune system.
Silymarin and Resveratrol — anti-inflammatories and antioxidants which also contribute to daytime photoprotection.
Trehalose and Triacetin — intense, long-lasting evening moisturisers.
Phytonadione — helps protect against broken capillary formation.
Lithium Magnesium Sodium Silicate — absorbs papule and pustule exudate, helps purify and soothe pores.
Evening use only.
Apply Rosacea Pre-Cleansing Emulsifier, rinse and follow with Rosacea Anti-Inflammatory Foaming Cleanser (all skin types), Rosacea Oil-Free Purifying Gel Cleanser (all skin types) or Rosacea Hydrating De-Sensitising Cleansing Emulsion (very dry skin).
Reminder: cleanse with tepid water and gently pat skin dry with a soft towel or by pressing tissues flat against the skin. Do not rub.
Apply a few drops of of Rosacea Anti-Inflammatory Clearing Serum and gently smooth in until completely absorbed.
Complete night care with Rosacea Intensive Night Nurturing Complex.
Massage in gently and allow product 10-15 minutes to set before retiring.
Suitable for use around the eyes. In case of ocular rosacea, apply Ocular Rosacea Soothing Serum underneath.
Use with Rosacea Medications
After preparing skin by cleansing in two steps as above, apply products in order of thinnest to thickest consistency, with Rosacea Intensive Night Nurturing Complex as the last step. For best results, wait 5-10 minutes inbetween layers.
Use nightly for 2 weeks, thereafter alternate use with Rosacea Treatment Fluid (all skin types), Rosacea Treatment Cream (drier skin types) or Rosacea Cooling Lotion (for environmental flare-ups).
Protect from heat in excess of 35°C/95°F.
Unopened shelf-life: 10 months.
Use within 4 months of opening.
Deuterium Oxide*, Glycerin*, D-Panthenol*, C12-20 Acid Peg-8 Ester, Squalene*, Cholesterol, Coco-Caprylate/Caprate, Biosaccharide Gum-1, Tridecyl Trimellitate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Alpha Tocopherol*, Linoleic Acid, Oleic Acid, Glycine*, Ilomastat, Polyglucuronate, Phospholipids, Neopentyl Glycol Dicaprylate/Dicaprate, Betaglucan, Schizophyllan, Ceramide AP, Ceramide NP, Phytosphingosine, Ceramide EOP, Sphingosine, Ceramide NS, Silybum Marianum Extract, Trehalose*, Triacetin*, Phytonadione*, Polygonum Cuspidatum (Resveratrol) Extract, Sebacic Acid, Lithium Magnesium Sodium Silicate, Lactitol*, Xylitol*.
Ingredients designated "*" meet Ph. Eur, BP and USP pharmaceutical standards.
Choi M, Maibach H. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dematol. 2005;6(4):215-23.
Meckfessel M, Brandt S. The structure, function, and importance of ceramides in skin and their use as therapeutic agents in skin-care products. J Am Acad Dermatol. 2014;71(1):177- 84.
Geilen C, Barz S, Bektas M. Sphingolipid Signaling in Epidermal Homeostasis. Skin Pharmacol Appl Skin Physiol. 2001;14:261-271.
Kwon Y, Kim C, Youm J, Gwak H, Park B, Lee S, Jeon S, Kim B, Seo Y, Park J, et al. Novel synthetic ceramide derivatives increase intracellular calcium levels and promote epidermal keratinocyte differentiation. J Lipid Res. 2007;48(9):1936-43.
Mojumdar E, Kariman Z, van Kerckhove L, Gooris G, Bouwstra J. The role of ceramide chain length distribution on the barrier properties of the skin lipid membranes. Biochim Biophys Acta. 2014;1838(10):2473-2483.
Vielhaber G, Pfeiffer S, Brade L, Lindner B, Goldmann T, Vollmer E, Hintze U, Wittern K, Wepf R. Localization of ceramide and glucosylceramide in human epidermis by immunogold electron microscopy. J Invest Deratol. 2001;117(5):1126-36.
Ilomastat — Merck Millipore.
Silymarin Monograph — Melbourne Dermatology.
Betaglucans Outline — Melbourne Dermatology.
Schwarz T. Biological effects of UV radiation on keratinocytes and Langerhans cells. Exp Dermatol. 2005;14(10):788-9.